Activity

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NR Protein	Protein Name	Ligand ID	Ligand Name	EC 50
NR1H4	Bile acid receptor	10046	3-[[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]benzoyl]amino]benzoic acid	3.0
NR1H4	Bile acid receptor	5695	3-[[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]benzoyl]-methylamino]benzoic acid	3.1
NR1H4	Bile acid receptor	5951	(2S)-1-[4-(4-methoxyphenyl)piperazin-1-yl]-3-(1,2,3,4,5,6,7,8-octahydrophenanthren-9-yloxy)propan-2-ol	3.15
NR1H4	Bile acid receptor	5751	propan‐2‐yl 2‐cyano‐4,4‐dimethyl‐6‐(oxane‐4‐ carbonyl)‐1H,4H,5H,6H,7H,8H‐pyrrolo[2,3‐d]azepine‐8‐ carboxylate	3.3
NR1H4	Bile acid receptor	5771	(4E)-1-(furan-2-carbonyl)-4-[(4-phenylmethoxyphenyl)methylidene]pyrazolidine-3,5-dione	3.31
NR1H4	Bile acid receptor	5909	2-[4-[3-[4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]-3-methylphenyl]pentan-3-yl]-2-methylphenoxy]acetic acid	3.4
NR1H4	Bile acid receptor	5765	(4E)-1-benzoyl-4-[(4-phenylmethoxyphenyl)methylidene]pyrazolidine-3,5-dione	3.98
NR1H4	Bile acid receptor	5863	6-[4-[[3-(3-chloro-1-methyl-6-oxopyridin-2-yl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]-2-methylphenyl]-1-methylindole-3-carboxylic acid	4.0
NR1H4	Bile acid receptor	5750	propan‐2‐yl 6‐(4‐chlorobenzoyl)‐2‐cyano‐4,4‐ dimethyl‐1H,4H,5H,6H,7H,8H‐pyrrolo[2,3‐d]azepine‐8‐ carboxylate	4.1
NR1H4	Bile acid receptor	5775	4-[(3-nitrophenyl)methylidene]-1,2-diphenylpyrazolidine-3,5-dione	4.27