10040 : 3-[(E)-2-[4-[[5-tert-butyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]-2-chlorophenyl]ethenyl]benzoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10040 |
| Name | 3-[(E)-2-[4-[[5-tert-butyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]-2-chlorophenyl]ethenyl]benzoic acid |
| smile | ClC1C=CC=C(C=1C1C(COC2C=CC(/C=C/C3C=CC=C(C(=O)O)C=3)=C(C=2)Cl)=C(C(C)(C)C)ON=1)Cl |
| weight | 557 |
| scaffold ID | 480 |
| scaffold smile | C(=Cc1ccc(OCc2conc2-c2ccccc2)cc1)c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H4 | Bile acid receptor | 10040 | 3-[(E)-2-[4-[[5-tert-butyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy]-2-chlorophenyl]ethenyl]benzoic acid | 1.3 |
Scaffold Activities Statistic