10044 : 3-[(E)-2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]-N-propylbenzamide
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10044 |
| Name | 3-[(E)-2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]-N-propylbenzamide |
| smile | ClC1C=CC=C(C=1C1C(COC2C=CC(/C=C/C3C=CC=C(C(NCCC)=O)C=3)=C(C=2)Cl)=C(C(C)C)ON=1)Cl |
| weight | 584 |
| scaffold ID | 480 |
| scaffold smile | C(=Cc1ccc(OCc2conc2-c2ccccc2)cc1)c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H4 | Bile acid receptor | 10044 | 3-[(E)-2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]-N-propylbenzamide | 9.0 |
Scaffold Activities Statistic