10045 : N,N-dibenzyl-3-[(E)-2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]benzamide
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10045 |
| Name | N,N-dibenzyl-3-[(E)-2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]benzamide |
| smile | ClC1C=CC=C(C=1C1C(COC2C=CC(/C=C/C3C=CC=C(C=3)C(N(CC3C=CC=CC=3)CC3C=CC=CC=3)=O)=C(C=2)Cl)=C(C(C)C)ON=1)Cl |
| weight | 722 |
| scaffold ID | 1214 |
| scaffold smile | O=C(c1cccc(C=Cc2ccc(OCc3conc3-c3ccccc3)cc2)c1)N(Cc1ccccc1)Cc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H4 | Bile acid receptor | 10045 | N,N-dibenzyl-3-[(E)-2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]benzamide | 35.1 |
Scaffold Activities Statistic