10186 : (E)-3-[3-(5-ethyl-4-oxo-2,3-dihydro-1H-cyclopenta[c]quinolin-8-yl)-4-(trifluoromethoxy)phenyl]prop-2-enoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10186 |
| Name | (E)-3-[3-(5-ethyl-4-oxo-2,3-dihydro-1H-cyclopenta[c]quinolin-8-yl)-4-(trifluoromethoxy)phenyl]prop-2-enoic acid |
| smile | FC(OC1C=CC(/C=C/C(=O)O)=CC=1C1C=CC2=C(C=1)C1=C(C(N2CC)=O)CCC1)(F)F |
| weight | 443 |
| scaffold ID | 183 |
| scaffold smile | O=c1[nH]c2ccc(-c3ccccc3)cc2c2c1CCC2 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR2B3 | Retinoid X receptor gamma | 10186 | (E)-3-[3-(5-ethyl-4-oxo-2,3-dihydro-1H-cyclopenta[c]quinolin-8-yl)-4-(trifluoromethoxy)phenyl]prop-2-enoic acid | 0.0966 |
Scaffold Activities Statistic