10187 : (5Z)-5-[[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]methylidene]-1,3-thiazolidine-2,4-dione
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10187 |
| Name | (5Z)-5-[[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]methylidene]-1,3-thiazolidine-2,4-dione |
| smile | S1C(NC(/C/1=C/C1C=CC(=C(C=1)C1C(C)=CC2=C(C=1)N(CC)C(CC2(C)C)=O)OC(F)(F)F)=O)=O |
| weight | 505 |
| scaffold ID | 182 |
| scaffold smile | O=C1NC(=O)C(=Cc2cccc(-c3ccc4c(c3)NC(=O)CC4)c2)S1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR2B3 | Retinoid X receptor gamma | 10187 | (5Z)-5-[[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]methylidene]-1,3-thiazolidine-2,4-dione | 0.0009 |
Scaffold Activities Statistic