10188 : (E)-3-[3-(4-ethyl-2,2,7-trimethyl-3-oxo-1,4-benzoxazin-6-yl)-4-(trifluoromethoxy)phenyl]but-2-enoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10188 |
| Name | (E)-3-[3-(4-ethyl-2,2,7-trimethyl-3-oxo-1,4-benzoxazin-6-yl)-4-(trifluoromethoxy)phenyl]but-2-enoic acid |
| smile | FC(OC1C=CC(/C(=C/C(=O)O)/C)=CC=1C1C(C)=CC2=C(C=1)N(CC)C(C(C)(C)O2)=O)(F)F |
| weight | 463 |
| scaffold ID | 184 |
| scaffold smile | O=C1COc2ccc(-c3ccccc3)cc2N1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR2B3 | Retinoid X receptor gamma | 10188 | (E)-3-[3-(4-ethyl-2,2,7-trimethyl-3-oxo-1,4-benzoxazin-6-yl)-4-(trifluoromethoxy)phenyl]but-2-enoic acid | 0.0612 |
Scaffold Activities Statistic