10190 : (E)-3-[3-(5-ethyl-4-oxo-2,3-dihydro-1H-cyclopenta[c]quinolin-7-yl)-4-(trifluoromethoxy)phenyl]prop-2-enoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10190 |
| Name | (E)-3-[3-(5-ethyl-4-oxo-2,3-dihydro-1H-cyclopenta[c]quinolin-7-yl)-4-(trifluoromethoxy)phenyl]prop-2-enoic acid |
| smile | FC(OC1C=CC(/C=C/C(=O)O)=CC=1C1C=CC2=C(C=1)N(CC)C(C1CCCC=12)=O)(F)F |
| weight | 443 |
| scaffold ID | 1306 |
| scaffold smile | O=c1[nH]c2cc(-c3ccccc3)ccc2c2c1CCC2 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR2B3 | Retinoid X receptor gamma | 10190 | (E)-3-[3-(5-ethyl-4-oxo-2,3-dihydro-1H-cyclopenta[c]quinolin-7-yl)-4-(trifluoromethoxy)phenyl]prop-2-enoic acid | 1.6 |
Scaffold Activities Statistic