10222 : 4-({butyl[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]amino}methyl)-2,6-dichlorophenol
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10222 |
| Name | 4-({butyl[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]amino}methyl)-2,6-dichlorophenol |
| smile | CCCCN(C1=CC=C(C(C(F)(F)F)(C(F)(F)F)O)C=C1)CC1=CC(=C(C(=C1)Cl)O)Cl |
| weight | 490 |
| scaffold ID | 247 |
| scaffold smile | c1ccc(CNc2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10222 | 4-({butyl[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]amino}methyl)-2,6-dichlorophenol | 3.0 |
Scaffold Activities Statistic