10252 : 3-(3-benzyl-8-chlorocinnolin-4-yl)-N-[(1-methyl-1H-indol-2-yl)methyl]aniline
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10252 |
| Name | 3-(3-benzyl-8-chlorocinnolin-4-yl)-N-[(1-methyl-1H-indol-2-yl)methyl]aniline |
| smile | CN1C(=CC2=CC=CC=C12)CNC1=CC=CC(C2=C(N=NC3=C(C=CC=C23)Cl)CC2=CC=CC=C2)=C1 |
| weight | 489 |
| scaffold ID | 155 |
| scaffold smile | c1c2ccccc2[nH]c1CNc1cccc(-c2c(Cc3ccccc3)nnc3ccccc32)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10252 | 3-(3-benzyl-8-chlorocinnolin-4-yl)-N-[(1-methyl-1H-indol-2-yl)methyl]aniline | 6.0 |
Scaffold Activities Statistic