10261 : 3-benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]phenyl}-8-(trifluoromethyl)cinnoline
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10261 |
| Name | 3-benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]phenyl}-8-(trifluoromethyl)cinnoline |
| smile | CN1C=CC2=CC=CC(=C12)COC1=CC=CC(C2=C(N=NC3=C(C(F)(F)F)C=CC=C23)CC2=CC=CC=C2)=C1 |
| weight | 524 |
| scaffold ID | 996 |
| scaffold smile | c1cc2cccc(COc3cccc(-c4c(Cc5ccccc5)nnc5ccccc54)c3)c2[nH]1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10261 | 3-benzyl-4-{3-[(1-methyl-1H-indol-7-yl)methoxy]phenyl}-8-(trifluoromethyl)cinnoline | 8.32 |
Scaffold Activities Statistic