10269 : 3-benzyl-4-(3-{[2-chloro-3-(trifluoromethyl)phenyl]methoxy}phenyl)-8-(trifluoromethyl)cinnoline
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10269 |
| Name | 3-benzyl-4-(3-{[2-chloro-3-(trifluoromethyl)phenyl]methoxy}phenyl)-8-(trifluoromethyl)cinnoline |
| smile | FC(C1=CC=CC(=C1Cl)COC1=CC=CC(C2=C(N=NC3=C(C(F)(F)F)C=CC=C23)CC2=CC=CC=C2)=C1)(F)F |
| weight | 573 |
| scaffold ID | 154 |
| scaffold smile | c1ccc(COc2cccc(-c3c(Cc4ccccc4)nnc4ccccc43)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10269 | 3-benzyl-4-(3-{[2-chloro-3-(trifluoromethyl)phenyl]methoxy}phenyl)-8-(trifluoromethyl)cinnoline | 18.1 |
Scaffold Activities Statistic