10325 : 3-{3-[8-chloro-2-(propan-2-yl)imidazo[1,2-a]pyridin-3-yl]phenoxy}-N-[(4-methoxyphenyl)methyl]-N-methylbenzene-1-sulfonamide
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10325 |
| Name | 3-{3-[8-chloro-2-(propan-2-yl)imidazo[1,2-a]pyridin-3-yl]phenoxy}-N-[(4-methoxyphenyl)methyl]-N-methylbenzene-1-sulfonamide |
| smile | COC1=CC=C(C=C1)CN(S(C1=CC=CC(=C1)OC1=CC=CC(C2=C(C(C)C)N=C3C(=CC=CN23)Cl)=C1)(=O)=O)C |
| weight | 576 |
| scaffold ID | 273 |
| scaffold smile | O=S(=O)(NCc1ccccc1)c1cccc(Oc2cccc(-c3cnc4ccccn43)c2)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10325 | 3-{3-[8-chloro-2-(propan-2-yl)imidazo[1,2-a]pyridin-3-yl]phenoxy}-N-[(4-methoxyphenyl)methyl]-N-methylbenzene-1-sulfonamide | 0.89 |
Scaffold Activities Statistic