10349 : 1-{3-[3-(3-methanesulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl}-1H-imidazole
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10349 |
| Name | 1-{3-[3-(3-methanesulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl}-1H-imidazole |
| smile | CS(C1=CC=CC(=C1)OC1=CC=CC(C2=C(N3C=CN=C3)N=C3C(C(F)(F)F)=CC=CN23)=C1)(=O)=O |
| weight | 498 |
| scaffold ID | 1187 |
| scaffold smile | c1cn(-c2nc3ccccn3c2-c2cccc(Oc3ccccc3)c2)cn1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10349 | 1-{3-[3-(3-methanesulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl}-1H-imidazole | 0.85 |
Scaffold Activities Statistic