10352 : 2-tert-butyl-3-[3-(3-methanesulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridine
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10352 |
| Name | 2-tert-butyl-3-[3-(3-methanesulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridine |
| smile | CC(C1N=C2C(C(F)(F)F)=CC=CN2C=1C1=CC=CC(=C1)OC1=CC=CC(S(C)(=O)=O)=C1)(C)C |
| weight | 489 |
| scaffold ID | 274 |
| scaffold smile | c1nc2ccccn2c1-c1cccc(Oc2ccccc2)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10352 | 2-tert-butyl-3-[3-(3-methanesulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridine | 0.71 |
Scaffold Activities Statistic