10358 : 3-({3-[3-(3-methanesulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl}methyl)-1,3-thiazolidine
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10358 |
| Name | 3-({3-[3-(3-methanesulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl}methyl)-1,3-thiazolidine |
| smile | CS(C1=CC=CC(=C1)OC1=CC=CC(C2=C(N=C3C(C(F)(F)F)=CC=CN23)CN2CCSC2)=C1)(=O)=O |
| weight | 534 |
| scaffold ID | 1259 |
| scaffold smile | c1ccc(Oc2cccc(-c3c(CN4CCSC4)nc4ccccn43)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10358 | 3-({3-[3-(3-methanesulfonylphenoxy)phenyl]-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl}methyl)-1,3-thiazolidine | 0.032 |
Scaffold Activities Statistic