10394 : 14-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-methyl-2-azatricyclo[10.4.0.0?,?]hexadeca-1(16),4,6,8,12,14-hexaen-3-one
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10394 |
| Name | 14-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-methyl-2-azatricyclo[10.4.0.0?,?]hexadeca-1(16),4,6,8,12,14-hexaen-3-one |
| smile | CN1C(C2=CC=CC=C2CCC2=CC(C(C(F)(F)F)(C(F)(F)F)O)=CC=C12)=O |
| weight | 403 |
| scaffold ID | 102 |
| scaffold smile | O=C1Nc2ccccc2CCc2ccccc21 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10394 | 14-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-methyl-2-azatricyclo[10.4.0.0?,?]hexadeca-1(16),4,6,8,12,14-hexaen-3-one | 0.91 |
Scaffold Activities Statistic