10431 : N-[(2-chloro-6-fluorophenyl)methyl]-N-{[4-(3-methanesulfonylphenyl)phenyl]methyl}-1-methyl-1H-imidazole-4-sulfonamide
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10431 |
| Name | N-[(2-chloro-6-fluorophenyl)methyl]-N-{[4-(3-methanesulfonylphenyl)phenyl]methyl}-1-methyl-1H-imidazole-4-sulfonamide |
| smile | CN1C=NC(S(N(CC2=C(C=CC=C2Cl)F)CC2=CC=C(C3=CC=CC(S(C)(=O)=O)=C3)C=C2)(=O)=O)=C1 |
| weight | 548 |
| scaffold ID | 743 |
| scaffold smile | O=S(=O)(c1c[nH]cn1)N(Cc1ccccc1)Cc1ccc(-c2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10431 | N-[(2-chloro-6-fluorophenyl)methyl]-N-{[4-(3-methanesulfonylphenyl)phenyl]methyl}-1-methyl-1H-imidazole-4-sulfonamide | 0.079 |
Scaffold Activities Statistic