10443 : (1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2R)-3,3-dimethyloxiran-2-yl]butan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10443 |
| Name | (1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2R)-3,3-dimethyloxiran-2-yl]butan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol |
| smile | CC(C1CCC2C1(C)CCC1C2CC=C2C1(C)CCC(O)C2)CCC1C(C)(C)O1 |
| weight | 401 |
| scaffold ID | 150 |
| scaffold smile | C1=C2CCCCC2C2CCC3C(CCCC4CO4)CCC3C2C1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10443 | (1S,2R,5S,10S,11S,14R,15R)-14-[(2R)-4-[(2R)-3,3-dimethyloxiran-2-yl]butan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol | 10.0 |
Scaffold Activities Statistic