10457 : methyl 4-(3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10457 |
| Name | methyl 4-(3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate |
| smile | CC(C1CCC2C1(C)CCC1C2CC=C2C1(C)CCC(O)C2)CCC(OC)=O |
| weight | 389 |
| scaffold ID | 149 |
| scaffold smile | C1=C2CCCCC2C2CCC3CCCC3C2C1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10457 | methyl 4-(3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate | 8.0 |
Scaffold Activities Statistic