10465 : N-(2,2,2-trifluoroethyl)-N-[4–(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)-phenyl]-benzenesulfonamide
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10465 |
| Name | N-(2,2,2-trifluoroethyl)-N-[4–(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)-phenyl]-benzenesulfonamide |
| smile | C1=CC=C(S(N(C2=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C2)CC(F)(F)F)(=O)=O)C=C1 |
| weight | 481 |
| scaffold ID | 123 |
| scaffold smile | O=S(=O)(Nc1ccccc1)c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10465 | N-(2,2,2-trifluoroethyl)-N-[4–(2,2,2-trifluoro-1-hydroxy-1-trifluoromethylethyl)-phenyl]-benzenesulfonamide | 0.02 |
Scaffold Activities Statistic