10490 : 2-(2,3-dimethoxyphenyl)-3-(5-fluoro-2-methylbenzoyl)-5-(4-fluorophenyl)-2,3-dihydro-1,3,4-thiadiazole
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10490 |
| Name | 2-(2,3-dimethoxyphenyl)-3-(5-fluoro-2-methylbenzoyl)-5-(4-fluorophenyl)-2,3-dihydro-1,3,4-thiadiazole |
| smile | CC1=C(C(N2C(C3=C(OC)C(OC)=CC=C3)SC(C3=CC=C(F)C=C3)=N2)=O)C=C(F)C=C1 |
| weight | 454 |
| scaffold ID | 417 |
| scaffold smile | O=C(c1ccccc1)N1N=C(c2ccccc2)SC1c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10490 | 2-(2,3-dimethoxyphenyl)-3-(5-fluoro-2-methylbenzoyl)-5-(4-fluorophenyl)-2,3-dihydro-1,3,4-thiadiazole | 2.4 |
Scaffold Activities Statistic