10504 : 2-[3-chloro-4-[ethyl(1,3-thiazol-4-ylmethyl)amino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 11)
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10504 |
| Name | 2-[3-chloro-4-[ethyl(1,3-thiazol-4-ylmethyl)amino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 11) |
| smile | CCN(C1=C(Cl)C=C(C(O)(C(F)(F)F)C(F)(F)F)C=C1)CC1=CSC=N1 |
| weight | 419 |
| scaffold ID | 1189 |
| scaffold smile | c1nc(CNc2ccccc2)cs1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10504 | 2-[3-chloro-4-[ethyl(1,3-thiazol-4-ylmethyl)amino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 11) | 0.5 |
Scaffold Activities Statistic