10511 : 2-[3-chloro-4-[[2-(3-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl-ethylamino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 18)
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10511 |
| Name | 2-[3-chloro-4-[[2-(3-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl-ethylamino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 18) |
| smile | CCN(C1=C(Cl)C=C(C(O)(C(F)(F)F)C(F)(F)F)C=C1)CC1=C(C)OC(C2=CC(Cl)=CC=C2)=N1 |
| weight | 527 |
| scaffold ID | 250 |
| scaffold smile | c1oc(-c2ccccc2)nc1CNc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10511 | 2-[3-chloro-4-[[2-(3-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl-ethylamino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 18) | 0.3 |
Scaffold Activities Statistic