10512 : 2-[4-[[2-(3-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl-(2,2,2-trifluoroethyl)amino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 19)
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10512 |
| Name | 2-[4-[[2-(3-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl-(2,2,2-trifluoroethyl)amino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 19) |
| smile | CC1=C(CN(C2=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C2)CC(F)(F)F)N=C(C2=CC(Cl)=CC=C2)O1 |
| weight | 547 |
| scaffold ID | 250 |
| scaffold smile | c1oc(-c2ccccc2)nc1CNc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10512 | 2-[4-[[2-(3-chlorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl-(2,2,2-trifluoroethyl)amino]phenyl]-1,1,1,3,3,3-hexafluoropropan-2-ol (anilinohexafluoroisopropanol 19) | 1.0 |
Scaffold Activities Statistic