10521 : 2-[N-ethyl-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)anilino]-1-morpholin-4-yl-2-phenylethanone (anilinohexafluoroisopropanol 32)
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10521 |
| Name | 2-[N-ethyl-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)anilino]-1-morpholin-4-yl-2-phenylethanone (anilinohexafluoroisopropanol 32) |
| smile | CCN(C(C(N1CCOCC1)=O)C1=CC=CC=C1)C1=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C1 |
| weight | 490 |
| scaffold ID | 837 |
| scaffold smile | O=C(C(Nc1ccccc1)c1ccccc1)N1CCOCC1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10521 | 2-[N-ethyl-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)anilino]-1-morpholin-4-yl-2-phenylethanone (anilinohexafluoroisopropanol 32) | 8.5 |
Scaffold Activities Statistic