10526 : methyl 1-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-phenylpyrrolidine-2-carboxylate (anilinohexafluoroisopropanol 37)
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10526 |
| Name | methyl 1-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-phenylpyrrolidine-2-carboxylate (anilinohexafluoroisopropanol 37) |
| smile | COC(C1(C2=CC=CC=C2)CCCN1C1=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C1)=O |
| weight | 447 |
| scaffold ID | 1327 |
| scaffold smile | c1ccc(C2CCCN2c2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10526 | methyl 1-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-2-phenylpyrrolidine-2-carboxylate (anilinohexafluoroisopropanol 37) | 0.2 |
Scaffold Activities Statistic