10575 : 2-[2-oxo-1-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]-3H-indol-5-yl]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 10575 |
| Name | 2-[2-oxo-1-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]-3H-indol-5-yl]acetic acid |
| smile | CCCC1=C(OCCCN2C(CC3=C2C=CC(CC(O)=O)=C3)=O)C=CC2=C1ON=C2C(F)(F)F |
| weight | 476 |
| scaffold ID | 119 |
| scaffold smile | O=C1Cc2ccccc2N1CCCOc1ccc2cnoc2c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 10575 | 2-[2-oxo-1-[3-[[7-propyl-3-(trifluoromethyl)-1,2-benzoxazol-6-yl]oxy]propyl]-3H-indol-5-yl]acetic acid | 0.18 |
Scaffold Activities Statistic