11105 : 2-(4-{[2-(anthracen-9-yl)-1-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethyl]sulfanyl}-2-methylphenoxy)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 11105 |
| Name | 2-(4-{[2-(anthracen-9-yl)-1-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethyl]sulfanyl}-2-methylphenoxy)acetic acid |
| smile | CC1=CC(=CC=C1OCC(O)=O)SC(C1SC(C2=CC=C(C(F)(F)F)C=C2)=NC=1C)CC1=C2C=CC=CC2=CC2=CC=CC=C12 |
| weight | 644 |
| scaffold ID | 256 |
| scaffold smile | c1nc(-c2ccccc2)sc1C(Cc1c2ccccc2cc2ccccc21)Sc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 11105 | 2-(4-{[2-(anthracen-9-yl)-1-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethyl]sulfanyl}-2-methylphenoxy)acetic acid | 10.0 |
Scaffold Activities Statistic