11228 : 2-[(1S)-5-(2-{5-methyl-2-[4-(propan-2-yl)phenyl]-1,3-thiazol-4-yl}ethoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 11228 |
| Name | 2-[(1S)-5-(2-{5-methyl-2-[4-(propan-2-yl)phenyl]-1,3-thiazol-4-yl}ethoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid |
| smile | CC(C1=CC=C(C2=NC(=C(S2)C)CCOC2=CC=C3[C@@H](CCC3=C2)CC(O)=O)C=C1)C |
| weight | 436 |
| scaffold ID | 353 |
| scaffold smile | c1sc(-c2ccccc2)nc1CCOc1ccc2c(c1)CCC2 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 11228 | 2-[(1S)-5-(2-{5-methyl-2-[4-(propan-2-yl)phenyl]-1,3-thiazol-4-yl}ethoxy)-2,3-dihydro-1H-inden-1-yl]acetic acid | 0.559 |
Scaffold Activities Statistic