1603 : (2S)-2-[(4-{2-[4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-2-methoxyphenyl]ethyl}phenyl)methyl]butanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 1603 |
| Name | (2S)-2-[(4-{2-[4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-2-methoxyphenyl]ethyl}phenyl)methyl]butanoic acid |
| smile | CC[C@H](C(O)=O)CC1=CC=C(C=C1)CCC1=CC=C(N2C(C3=CC=CC=C3C2=O)=O)C=C1OC |
| weight | 458 |
| scaffold ID | 146 |
| scaffold smile | O=C1c2ccccc2C(=O)N1c1ccc(CCc2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 1603 | (2S)-2-[(4-{2-[4-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-2-methoxyphenyl]ethyl}phenyl)methyl]butanoic acid | 7.3 |
Scaffold Activities Statistic