1637 : 2-{2-ethyl-4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}-2-fluoroacetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 1637 |
| Name | 2-{2-ethyl-4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}-2-fluoroacetic acid |
| smile | CCC1=CC(=CC=C1OC(C(O)=O)F)SCC1SC(C2=CC=C(C(F)(F)F)C=C2)=NC=1C |
| weight | 486 |
| scaffold ID | 64 |
| scaffold smile | c1nc(-c2ccccc2)sc1CSc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 1637 | 2-{2-ethyl-4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}-2-fluoroacetic acid | 0.29 |
Scaffold Activities Statistic