1719 : 2-{4-[(2-cyclopropyl-1-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethyl)sulfanyl]-2-methylphenoxy}acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 1719 |
| Name | 2-{4-[(2-cyclopropyl-1-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethyl)sulfanyl]-2-methylphenoxy}acetic acid |
| smile | CC1=CC(=CC=C1OCC(O)=O)SC(C1SC(C2=CC=C(C(F)(F)F)C=C2)=NC=1C)CC1CC1 |
| weight | 508 |
| scaffold ID | 166 |
| scaffold smile | c1nc(-c2ccccc2)sc1C(CC1CC1)Sc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 1719 | 2-{4-[(2-cyclopropyl-1-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}ethyl)sulfanyl]-2-methylphenoxy}acetic acid | 0.001 |
Scaffold Activities Statistic