1726 : 2-{2-methyl-4-[(1-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}-2-(4-phenylphenyl)ethyl)sulfanyl]phenoxy}acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 1726 |
| Name | 2-{2-methyl-4-[(1-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}-2-(4-phenylphenyl)ethyl)sulfanyl]phenoxy}acetic acid |
| smile | CC1=CC(=CC=C1OCC(O)=O)SC(C1SC(C2=CC=C(C(F)(F)F)C=C2)=NC=1C)CC1=CC=C(C2=CC=CC=C2)C=C1 |
| weight | 620 |
| scaffold ID | 1268 |
| scaffold smile | c1nc(-c2ccccc2)sc1C(Cc1ccc(-c2ccccc2)cc1)Sc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 1726 | 2-{2-methyl-4-[(1-{4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}-2-(4-phenylphenyl)ethyl)sulfanyl]phenoxy}acetic acid | 0.004 |
Scaffold Activities Statistic