1767 : ethyl 2-[3-hydroxy-5-(5-methylfuran-2-yl)-2-oxo-4-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 1767 |
| Name | ethyl 2-[3-hydroxy-5-(5-methylfuran-2-yl)-2-oxo-4-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate |
| smile | CCOC(C1SC(N2C(C3OC(=CC=3)C)C(C(C3=CC=CS3)=O)=C(C2=O)O)=NC=1C)=O |
| weight | 459 |
| scaffold ID | 137 |
| scaffold smile | O=C(c1cccs1)C1=CC(=O)N(c2nccs2)C1c1ccco1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 1767 | ethyl 2-[3-hydroxy-5-(5-methylfuran-2-yl)-2-oxo-4-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-1-yl]-4-methyl-1,3-thiazole-5-carboxylate | 26.0 |
Scaffold Activities Statistic