1882 : (2R)-3-[4-[(E)-5-[7-[(E)-5-[4-[(2R)-2-carboxy-2-ethoxyethyl]phenoxy]-3-methylpent-3-en-1-ynyl]-9-oxofluoren-2-yl]-3-methylpent-2-en-4-ynoxy]phenyl]-2-ethoxypropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 1882 |
| Name | (2R)-3-[4-[(E)-5-[7-[(E)-5-[4-[(2R)-2-carboxy-2-ethoxyethyl]phenoxy]-3-methylpent-3-en-1-ynyl]-9-oxofluoren-2-yl]-3-methylpent-2-en-4-ynoxy]phenyl]-2-ethoxypropanoic acid |
| smile | O=C1C2C=C(C#C/C(/C)=C/COC3C=CC(=CC=3)C[C@H](C(=O)O)OCC)C=CC=2C2C=CC(C#C/C(/C)=C/COC3C=CC(=CC=3)C[C@H](C(=O)O)OCC)=CC=21 |
| weight | 753 |
| scaffold ID | 819 |
| scaffold smile | O=C1c2cc(C#CC=CCOc3ccccc3)ccc2-c2ccc(C#CC=CCOc3ccccc3)cc21 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 1882 | (2R)-3-[4-[(E)-5-[7-[(E)-5-[4-[(2R)-2-carboxy-2-ethoxyethyl]phenoxy]-3-methylpent-3-en-1-ynyl]-9-oxofluoren-2-yl]-3-methylpent-2-en-4-ynoxy]phenyl]-2-ethoxypropanoic acid | 1.1 |
Scaffold Activities Statistic