2199 : 2-methyl-2-[4-[[[4-methyl-2-(4-oxocyclohexa-2,5-dien-1-ylidene)-3H-1,3-thiazole-5-carbonyl]amino]methyl]phenoxy]propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 2199 |
| Name | 2-methyl-2-[4-[[[4-methyl-2-(4-oxocyclohexa-2,5-dien-1-ylidene)-3H-1,3-thiazole-5-carbonyl]amino]methyl]phenoxy]propanoic acid |
| smile | S1/C(=C2\C=CC(C=C\2)=O)/NC(C)=C1C(NCC1C=CC(=CC=1)OC(C(=O)O)(C)C)=O |
| weight | 426 |
| scaffold ID | 868 |
| scaffold smile | O=C(NCc1ccccc1)C1=CNC(=C2C=CC(=O)C=C2)S1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 2199 | 2-methyl-2-[4-[[[4-methyl-2-(4-oxocyclohexa-2,5-dien-1-ylidene)-3H-1,3-thiazole-5-carbonyl]amino]methyl]phenoxy]propanoic acid | 10.0 |
Scaffold Activities Statistic