2570 : 3-{5-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-2-[(prop-2-yn-1-yloxy)carbonyl]-1,2,3,4-tetrahydroisoquinolin-8-yl}propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 2570 |
| Name | 3-{5-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-2-[(prop-2-yn-1-yloxy)carbonyl]-1,2,3,4-tetrahydroisoquinolin-8-yl}propanoic acid |
| smile | CC1OC(C2=CC=CC=C2)=NC=1CCOC1=CC=C(C2CN(C(OCC#C)=O)CCC1=2)CCC(O)=O |
| weight | 489 |
| scaffold ID | 540 |
| scaffold smile | c1oc(-c2ccccc2)nc1CCOc1cccc2c1CCNC2 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 2570 | 3-{5-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-2-[(prop-2-yn-1-yloxy)carbonyl]-1,2,3,4-tetrahydroisoquinolin-8-yl}propanoic acid | 3.021 |
Scaffold Activities Statistic