2640 : 2-[(8-{[(4-{[4-(trifluoromethyl)phenyl]methoxy}phenyl)methyl]sulfanyl}-3,4-dihydro-2H-1-benzopyran-5-yl)oxy]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 2640 |
| Name | 2-[(8-{[(4-{[4-(trifluoromethyl)phenyl]methoxy}phenyl)methyl]sulfanyl}-3,4-dihydro-2H-1-benzopyran-5-yl)oxy]acetic acid |
| smile | OC(COC1=CC=C(C2OCCCC1=2)SCC1=CC=C(C=C1)OCC1=CC=C(C(F)(F)F)C=C1)=O |
| weight | 505 |
| scaffold ID | 1049 |
| scaffold smile | c1ccc(COc2ccc(CSc3cccc4c3OCCC4)cc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 2640 | 2-[(8-{[(4-{[4-(trifluoromethyl)phenyl]methoxy}phenyl)methyl]sulfanyl}-3,4-dihydro-2H-1-benzopyran-5-yl)oxy]acetic acid | 0.295 |
Scaffold Activities Statistic