2812 : 4-methyl-N-{[4-(4-methylbenzenesulfonamido)phenyl]methyl}-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 2812 |
| Name | 4-methyl-N-{[4-(4-methylbenzenesulfonamido)phenyl]methyl}-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide |
| smile | CC1=CC=C(S(NC2=CC=C(C=C2)CNC(C2SC(C3=CC=C(C(F)(F)F)C=C3)=NC=2C)=O)(=O)=O)C=C1 |
| weight | 546 |
| scaffold ID | 844 |
| scaffold smile | O=C(NCc1ccc(NS(=O)(=O)c2ccccc2)cc1)c1cnc(-c2ccccc2)s1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 2812 | 4-methyl-N-{[4-(4-methylbenzenesulfonamido)phenyl]methyl}-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide | 10.0 |
Scaffold Activities Statistic