2813 : (2E)-3-[2-methyl-4-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methoxy)phenyl]prop-2-enoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 2813 |
| Name | (2E)-3-[2-methyl-4-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methoxy)phenyl]prop-2-enoic acid |
| smile | CC1=CC(=CC=C1/C=C/C(O)=O)OCC1SC(C2=CC=C(C(F)(F)F)C=C2)=NC=1C |
| weight | 433 |
| scaffold ID | 577 |
| scaffold smile | c1nc(-c2ccccc2)sc1COc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 2813 | (2E)-3-[2-methyl-4-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methoxy)phenyl]prop-2-enoic acid | 2.7 |
Scaffold Activities Statistic