2817 : 2-[4-({[3-(3-chloro-4-methylphenyl)-1,2,4-thiadiazol-5-yl]methyl}sulfanyl)-2-methylphenoxy]-2-methylpropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 2817 |
| Name | 2-[4-({[3-(3-chloro-4-methylphenyl)-1,2,4-thiadiazol-5-yl]methyl}sulfanyl)-2-methylphenoxy]-2-methylpropanoic acid |
| smile | CC1=CC=C(C2=NSC(=N2)CSC2=CC=C(C(=C2)C)OC(C(O)=O)(C)C)C=C1Cl |
| weight | 449 |
| scaffold ID | 411 |
| scaffold smile | c1ccc(SCc2nc(-c3ccccc3)ns2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 2817 | 2-[4-({[3-(3-chloro-4-methylphenyl)-1,2,4-thiadiazol-5-yl]methyl}sulfanyl)-2-methylphenoxy]-2-methylpropanoic acid | 0.669 |
Scaffold Activities Statistic