2819 : 2-methyl-2-{2-methyl-4-[(2-{3-[4-(trifluoromethyl)phenyl]-1,2,4-thiadiazol-5-yl}ethyl)sulfanyl]phenoxy}propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 2819 |
| Name | 2-methyl-2-{2-methyl-4-[(2-{3-[4-(trifluoromethyl)phenyl]-1,2,4-thiadiazol-5-yl}ethyl)sulfanyl]phenoxy}propanoic acid |
| smile | CC1=CC(=CC=C1OC(C(O)=O)(C)C)SCCC1=NC(C2=CC=C(C(F)(F)F)C=C2)=NS1 |
| weight | 483 |
| scaffold ID | 528 |
| scaffold smile | c1ccc(SCCc2nc(-c3ccccc3)ns2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 2819 | 2-methyl-2-{2-methyl-4-[(2-{3-[4-(trifluoromethyl)phenyl]-1,2,4-thiadiazol-5-yl}ethyl)sulfanyl]phenoxy}propanoic acid | 0.465 |
Scaffold Activities Statistic