2853 : 2-methyl-2-{[1-(3-{[1-propyl-6-(pyridine-4-carbonyl)naphthalen-2-yl]oxy}propyl)-1H-indol-5-yl]oxy}propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 2853 |
| Name | 2-methyl-2-{[1-(3-{[1-propyl-6-(pyridine-4-carbonyl)naphthalen-2-yl]oxy}propyl)-1H-indol-5-yl]oxy}propanoic acid |
| smile | CCCC1=C(C=CC2=CC(C(C3=CC=NC=C3)=O)=CC=C12)OCCCN1C=CC2=CC(=CC=C12)OC(C(O)=O)(C)C |
| weight | 551 |
| scaffold ID | 532 |
| scaffold smile | O=C(c1ccncc1)c1ccc2cc(OCCCn3ccc4ccccc43)ccc2c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 2853 | 2-methyl-2-{[1-(3-{[1-propyl-6-(pyridine-4-carbonyl)naphthalen-2-yl]oxy}propyl)-1H-indol-5-yl]oxy}propanoic acid | 2.07 |
Scaffold Activities Statistic