2887 : 2-methyl-2-{2-methyl-4-[({1-methyl-5-[4-(pyridin-4-yl)phenyl]-1H-pyrazol-3-yl}formamido)methyl]phenoxy}propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 2887 |
| Name | 2-methyl-2-{2-methyl-4-[({1-methyl-5-[4-(pyridin-4-yl)phenyl]-1H-pyrazol-3-yl}formamido)methyl]phenoxy}propanoic acid |
| smile | CC1=CC(=CC=C1OC(C(O)=O)(C)C)CNC(C1C=C(N(N=1)C)C1=CC=C(C2=CC=NC=C2)C=C1)=O |
| weight | 485 |
| scaffold ID | 341 |
| scaffold smile | O=C(NCc1ccccc1)c1cc(-c2ccc(-c3ccncc3)cc2)[nH]n1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 2887 | 2-methyl-2-{2-methyl-4-[({1-methyl-5-[4-(pyridin-4-yl)phenyl]-1H-pyrazol-3-yl}formamido)methyl]phenoxy}propanoic acid | 0.31 |
Scaffold Activities Statistic