2945 : 2-(2,3-dimethyl-4-{[2-(oxolan-2-ylmethoxy)-4-[4-(trifluoromethyl)phenoxymethyl]phenyl]sulfanyl}phenoxy)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 2945 |
| Name | 2-(2,3-dimethyl-4-{[2-(oxolan-2-ylmethoxy)-4-[4-(trifluoromethyl)phenoxymethyl]phenyl]sulfanyl}phenoxy)acetic acid |
| smile | CC1=C(C(=CC=C1OCC(O)=O)SC1=CC=C(C=C1OCC1CCCO1)COC1=CC=C(C(F)(F)F)C=C1)C |
| weight | 563 |
| scaffold ID | 860 |
| scaffold smile | c1ccc(OCc2ccc(Sc3ccccc3)c(OCC3CCCO3)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 2945 | 2-(2,3-dimethyl-4-{[2-(oxolan-2-ylmethoxy)-4-[4-(trifluoromethyl)phenoxymethyl]phenyl]sulfanyl}phenoxy)acetic acid | 10.0 |
Scaffold Activities Statistic