2946 : 2-[(4-{[2-(pent-2-yn-1-yloxy)-4-({[5-(trifluoromethyl)pyridin-2-yl]oxy}methyl)phenyl]sulfanyl}-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 2946 |
| Name | 2-[(4-{[2-(pent-2-yn-1-yloxy)-4-({[5-(trifluoromethyl)pyridin-2-yl]oxy}methyl)phenyl]sulfanyl}-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]acetic acid |
| smile | CCC#CCOC1=CC(=CC=C1SC1=CC=C(C2CCCCC1=2)OCC(O)=O)COC1=CC=C(C(F)(F)F)C=N1 |
| weight | 572 |
| scaffold ID | 1054 |
| scaffold smile | c1ccc(OCc2ccc(Sc3cccc4c3CCCC4)cc2)nc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 2946 | 2-[(4-{[2-(pent-2-yn-1-yloxy)-4-({[5-(trifluoromethyl)pyridin-2-yl]oxy}methyl)phenyl]sulfanyl}-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]acetic acid | 0.49 |
Scaffold Activities Statistic