2988 : 2-[2,3-dimethyl-4-({2-[2-(morpholin-4-yl)ethoxy]-4-[4-(trifluoromethyl)phenoxymethyl]phenyl}sulfanyl)phenoxy]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 2988 |
| Name | 2-[2,3-dimethyl-4-({2-[2-(morpholin-4-yl)ethoxy]-4-[4-(trifluoromethyl)phenoxymethyl]phenyl}sulfanyl)phenoxy]acetic acid |
| smile | CC1=C(C(=CC=C1OCC(O)=O)SC1=CC=C(C=C1OCCN1CCOCC1)COC1=CC=C(C(F)(F)F)C=C1)C |
| weight | 592 |
| scaffold ID | 293 |
| scaffold smile | c1ccc(OCc2ccc(Sc3ccccc3)c(OCCN3CCOCC3)c2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 2988 | 2-[2,3-dimethyl-4-({2-[2-(morpholin-4-yl)ethoxy]-4-[4-(trifluoromethyl)phenoxymethyl]phenyl}sulfanyl)phenoxy]acetic acid | 10.0 |
Scaffold Activities Statistic