2992 : 2-[2,3-dimethyl-4-({2-[(5-methyl-1,2-oxazol-3-yl)methoxy]-4-[4-(trifluoromethyl)phenoxymethyl]phenyl}sulfanyl)phenoxy]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 2992 |
| Name | 2-[2,3-dimethyl-4-({2-[(5-methyl-1,2-oxazol-3-yl)methoxy]-4-[4-(trifluoromethyl)phenoxymethyl]phenyl}sulfanyl)phenoxy]acetic acid |
| smile | CC1ON=C(C=1)COC1=CC(=CC=C1SC1=CC=C(C(=C1C)C)OCC(O)=O)COC1=CC=C(C(F)(F)F)C=C1 |
| weight | 574 |
| scaffold ID | 291 |
| scaffold smile | c1cc(COc2cc(COc3ccccc3)ccc2Sc2ccccc2)no1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 2992 | 2-[2,3-dimethyl-4-({2-[(5-methyl-1,2-oxazol-3-yl)methoxy]-4-[4-(trifluoromethyl)phenoxymethyl]phenyl}sulfanyl)phenoxy]acetic acid | 10.0 |
Scaffold Activities Statistic