3067 : (2R)-3-[4-(2-{6-[(1E)-(methoxyimino)(phenyl)methyl]-4,4-dimethyl-1,2,3,4-tetrahydroquinolin-1-yl}ethoxy)phenyl]-2-(2,2,2-trifluoroethoxy)propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 3067 |
| Name | (2R)-3-[4-(2-{6-[(1E)-(methoxyimino)(phenyl)methyl]-4,4-dimethyl-1,2,3,4-tetrahydroquinolin-1-yl}ethoxy)phenyl]-2-(2,2,2-trifluoroethoxy)propanoic acid |
| smile | CO/N=C(/C1=CC=C2N(CCC(C2=C1)(C)C)CCOC1=CC=C(C=C1)C[C@H](C(O)=O)OCC(F)(F)F)\C1=CC=CC=C1 |
| weight | 585 |
| scaffold ID | 486 |
| scaffold smile | N=C(c1ccccc1)c1ccc2c(c1)CCCN2CCOc1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 3067 | (2R)-3-[4-(2-{6-[(1E)-(methoxyimino)(phenyl)methyl]-4,4-dimethyl-1,2,3,4-tetrahydroquinolin-1-yl}ethoxy)phenyl]-2-(2,2,2-trifluoroethoxy)propanoic acid | 0.125 |
Scaffold Activities Statistic